Are these alternatives therapeutically equivalent?

Generics with the same INN have the same active substance and are assessed by the European Medicines Agency (EMA) for bioequivalence. Differences appear in the excipients (relevant for patients with specific food allergies — e.g. lactose), the brand and the manufacturer. Even so, the decision to switch rests with the doctor or pharmacist; do not change a chronic treatment without consultation.

Can I replace Caldefix 1000mg/ 880 ui, 20 comprimate efervescente, Recordati with a generic without consulting the doctor?

For OTC (over-the-counter) medicines you can ask the pharmacist for an alternative with the same INN — this is accepted practice. For prescription medicines, substitution happens either through an INN prescription (the doctor prescribes the active substance, not the brand) or with the doctor's agreement. HartaFarmacii shows alternatives for information — this is not a medical recommendation.

Cheaper alternatives to Caldefix 1000mg/ 880 ui, 20 comprimate efervescente, Recordati

In short: for Caldefix 1000mg/ 880 ui, 20 comprimate efervescente, Recordati (active substance: COMBINATII) there are 10 equivalent medicines with the same INN on HartaFarmacii, 10 of which are cheaper than the current product. The cheapest alternative is FARINGOSEPT COMBO MIERE SI LAMAIE 0,6 mg/1,2 mg, at 11.20 RON — 21.79 RON below the reference price of 32.99 RON. Equivalents with the same INN contain the same active substance, but switching a treatment requires the doctor's agreement — ask the pharmacist before any substitution.

For the active substance COMBINATII 1000mg, we found 10 equivalent medicines with the same INN, with prices updated daily. Reference price for Caldefix 1000mg/ 880 ui, 20 comprimate efervescente, Recordati: 32.99 RON.

Cheapest alternative: FARINGOSEPT COMBO MIERE SI LAMAIE 0,6 mg/1,2 mg

11.20 RON

You save 21.79 RON compared with Caldefix 1000mg/ 880 ui, 20 comprimate efervescente, Recordati Manufacturer/brand: Terapia Sa · 0,6mg/1,2mg · PASTILE See the full page: FARINGOSEPT COMBO MIERE SI LAMAIE 0,6 mg/1,2 mg →

Generics with the same INN

The same active substance (COMBINATII), a different brand or manufacturer. Sorted by price, lowest first.

Generic vs original — in short

Generics contain the same active substance (INN) as the original product, at the same dose and in the same pharmaceutical form. To be authorised they must demonstrate bioequivalence — that is, a similar pharmacokinetic profile (the blood concentration over time is within ±20%). Typical differences are in the excipients (relevant for patients allergic to lactose, gluten or colourings), the brand and the manufacturer. For chronic treatments, switching from one generic to another is done with the doctor's agreement — even if the active substance is identical, individual tolerance can differ.

Alternatives from the same category

A different INN, but the same therapeutic category — Vitamine si minerale. These are NOT direct substitutes; consult the doctor or pharmacist.

Frequently asked questions

Which alternative to Caldefix 1000mg/ 880 ui, 20 comprimate efervescente, Recordati is the cheapest?

FARINGOSEPT COMBO MIERE SI LAMAIE 0,6 mg/1,2 mg is the cheapest same-INN alternative listed — 11.20 RON, 21.79 RON below the current price of Caldefix 1000mg/ 880 ui, 20 comprimate efervescente, Recordati. It contains the same active substance (COMBINATII); the brand, the pack and sometimes the excipients differ.
Are these alternatives therapeutically equivalent?

Generics with the same INN have the same active substance and are assessed by the European Medicines Agency (EMA) for bioequivalence. Differences appear in the excipients (relevant for patients with specific food allergies — e.g. lactose), the brand and the manufacturer. Even so, the decision to switch rests with the doctor or pharmacist; do not change a chronic treatment without consultation.
Can I replace Caldefix 1000mg/ 880 ui, 20 comprimate efervescente, Recordati with a generic without consulting the doctor?

For OTC (over-the-counter) medicines you can ask the pharmacist for an alternative with the same INN — this is accepted practice. For prescription medicines, substitution happens either through an INN prescription (the doctor prescribes the active substance, not the brand) or with the doctor's agreement. HartaFarmacii shows alternatives for information — this is not a medical recommendation.

The lists of alternatives are built automatically from the INN field and the therapeutic category in our database — they are NOT a medical recommendation. For therapeutic substitution, consult the doctor or pharmacist. See the methodology and the editorial team.