4 recommended OTC medicines
8,930 pharmacies available

In short: A headache (cephalalgia) is one of the most common symptoms: nearly every adult experiences one at least once a year, and most episodes ease with rest and an over-the-counter painkiller such as paracetamol, ibuprofen, acetylsalicylic acid or naproxen. On HartaFarmacii you can compare the price of these OTC options across the major pharmacy chains (Dr. Max, Tei, Catena, HelpNet), with prices updated daily. This information is for guidance only and does not replace a medical consultation; seek emergency care if you have a sudden, very severe headache that feels like the worst of your life.

Data verified on from public sources (OpenStreetMap, chain websites, ANM/MS) — updated daily.

OTC — no prescription

What can you take for headache?

Informational only — HartaFarmacii is not an approved medical site. Talk to your doctor or pharmacist before taking any medicine. Don't self-medicate. Emergencies: 112.

When to see a doctor

If any of these signs appear, see a doctor — OTC treatment is not enough:

  • Sudden, very intense pain (the worst pain of your life)
  • Pain after a head injury
  • Pain accompanied by high fever, neck stiffness
  • Disturbances of vision, speech or movement
  • New headache after the age of 50
  • Pain that consistently wakes you from sleep

Types of headache and how to recognise them

Tension headache is the most common form — it appears as bilateral pressure, like a tight band around the head, of mild or moderate intensity. It usually appears in the evening, after a long day at the office, and is not aggravated by ordinary physical activity.

Migraine is different: a throbbing pain, usually one-sided, accompanied by nausea, sensitivity to light and noise, lasting 4-72 hours. Cluster headache is a rare but extremely intense form, localised around one eye.

Secondary headache arises from another cause — sinusitis, hypertension, dehydration, alcohol consumption, sleep apnoea, chronic use of painkillers. If the pain is new, unusual or worsens rapidly, the cause must be investigated.

What you can take for an occasional headache

For a mild-to-moderate tension headache, paracetamol 500-1000 mg is the first choice — a good safety profile, it does not irritate the stomach. The maximum dose in adults is 4 g/24h, and less in people with liver impairment.

Ibuprofen 200-400 mg is an effective alternative, especially when there is also an inflammatory component (sinus, muscular). It is taken with food to protect the stomach and is contraindicated in people with ulcers, kidney disease or in the last trimester of pregnancy.

Acetylsalicylic acid (aspirin) 500 mg remains effective, but it is not given to children under 16 (risk of Reye's syndrome). Combinations with caffeine (paracetamol + aspirin + caffeine) act more quickly.

Golden rules for OTC painkillers

  • Do not exceed the recommended doses and do not combine two NSAIDs at the same time.
  • Do not take painkillers for more than 10-15 days a month — risk of medication-overuse headache (MOH).
  • Stay hydrated: many headaches disappear after 500 ml of water.
  • If the pain returns within 4h, increasing the dose in an adult is safer than a second dose within a short interval — but respect the MDD.

Non-pharmacological measures that work

Rest in a dark room, apply a cold compress to the forehead or a warm one to the nape, try deep-breathing techniques. A mint or chamomile tea can help, as can a handful of almonds (magnesium helps with migraine).

For chronic headache, keep a diary — you identify the triggers (stress, sleep, food, hormonal cycle) and can prevent the episodes.

When to see a doctor

Some headaches are warning signs and must not be ignored. See the dedicated section below for the full list of symptoms that require immediate evaluation.

For recurrent headache or one that affects your quality of life, talk to your family doctor — there are effective preventive treatments (beta-blockers, topiramate, triptans for migraine) that are not OTC but can make the difference.

Medical disclaimer: the information in this guide is for informational purposes and does not replace the advice of a doctor or pharmacist. For diagnosis and treatment, consult a health professional.

Medicines compared

Medicines used for headache

This list is for guidance only, generated automatically from the DCI/category match. It is not a medical recommendation — consult your doctor before starting any treatment.

This list is not a medical recommendation. Consult your doctor or pharmacist.

Night-time, weekends, public holidays

24/7 pharmacies for headache

Headache doesn't keep office hours. If you need a medicine at 2 a.m. or at the weekend, open the map with the 24/7 filter switched on and look for the nearest on-duty pharmacy. Large cities have dozens of pharmacies open around the clock — below you have direct access to the list for each city, with address, phone number and verified opening hours.

Call before you set off, especially at night — on-duty rotas change and stock of some prescription medicines can be limited between deliveries.

Search the pharmacy

Medicine categories for headache

Step by step

How to find a pharmacy fast for headache

Open the interactive map and allow location access — you will immediately see pharmacies sorted by distance, each with its opening hours and a one-tap route in Google Maps. If it is night or the weekend, switch on the 24/7 filter to keep only the on-duty ones. For headache many medicines are available over the counter, so you can go straight to the pharmacy without a prescription, but check availability on the price comparator first to avoid wasted trips.

If you have a preferred active substance (for example paracetamol or ibuprofen), search for it in the comparator before you leave — you will see which chain has it cheapest near you and whether it is in stock. If you have a repeat prescription, save your preferred pharmacy as a favourite in the app and turn on opening-hours notifications — it saves unnecessary trips, especially if treatment for headache goes on for a while.

See also

Related symptoms and conditions

Frequently asked questions

What else would you like to know?

How much paracetamol can I take for a headache?
In adults, 500-1000 mg per dose, with at least 4-6h between doses, maximum 4 g/24h. In people with liver impairment, maximum 2-3 g/24h.
Is paracetamol or ibuprofen better for a headache?
For an ordinary tension headache both are effective. Paracetamol is safer for the stomach, ibuprofen more effective when there is inflammation (sinusitis, cervical muscle pain).
Can I take paracetamol and ibuprofen together?
Yes, they can be combined — they act through different pathways. However, do not combine two NSAIDs (ibuprofen + aspirin or ibuprofen + naproxen).
Why do I have headaches every day?
Common causes: chronic stress, sleep disorders, dehydration, caffeine overuse, eye strain or medication-overuse headache (more than 10 days/month with OTC). It is worth a medical evaluation.
What do I do if the painkiller doesn't help me?
Do not double the dose above the MDD. Try resting in a dark room, hydration, a cold compress. If the pain persists beyond 24h or worsens, see a doctor.

See also

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