6 recommended OTC medicines
8,930 pharmacies available

In short: A sprain is a ligament injury caused by sudden overstretching or tearing, most often at the ankle, and is managed at first with rest, ice and compression. For pain and swelling, OTC options range from oral anti-inflammatories (ibuprofen, naproxen, paracetamol) to topical gels such as diclofenac, arnica or heparinoid. On HartaFarmacii you can compare the price of these products across Dr. Max, Tei, Catena and HelpNet, with prices updated daily. This information is for guidance only and does not replace medical advice; see a doctor if you cannot bear any weight on the leg.

Data verified on from public sources (OpenStreetMap, chain websites, ANM/MS) — updated daily.

OTC — no prescription

What can you take for sprain?

Informational only — HartaFarmacii is not an approved medical site. Talk to your doctor or pharmacist before taking any medicine. Don't self-medicate. Emergencies: 112.

When to see a doctor

If any of these signs appear, see a doctor — OTC treatment is not enough:

  • Complete inability to step on the limb
  • Obvious deformity of the joint
  • Severe progressive pain
  • A noise at the moment of injury (a snap, a pop)
  • Massive swelling within the first hour
  • Distal numbness, absent pulse

Immediate treatment — the RICE protocol

Rest — avoid putting weight on the affected area for 24-48h. Ice — 15-20 min every 2-3h, for a maximum of 48h. Compression — elastic bandage. Elevation — raise the limb above the level of the heart.

OTC treatment

Oral NSAIDs — ibuprofen 400 mg, naproxen 500 mg for pain and inflammation. During the first 48h there is a theory that NSAIDs may slow healing — controversial; they may be used in moderation.

Topical NSAIDs — diclofenac gel, ibuprofen gel 3-4 times/day.

Braces, elastic bandages — support for the joint.

Creams with arnica, heparinoid — reduce the bruising and swelling.

Paracetamol — if NSAIDs are contraindicated.

Recovery

  • Days 1-3: RICE + analgesic.
  • Days 3-7: passive mobilization, then light active mobilization.
  • Days 7-21: progressive strengthening exercises.
  • Return to sport: at full strength and without pain on specific maneuvers.

When to see a doctor/emergency care

Inability to bear weight on the limb, obvious deformity, severe progressive pain, a noise at the moment of injury (a pop), rapid massive swelling, distal numbness — all of these require an X-ray (to rule out a fracture).

Medical disclaimer: the information in this guide is for informational purposes and does not replace the advice of a doctor or pharmacist. For diagnosis and treatment consult a healthcare professional.

Medicines compared

Medicines used for sprain

This list is for guidance only, generated automatically from the DCI/category match. It is not a medical recommendation — consult your doctor before starting any treatment.

This list is not a medical recommendation. Consult your doctor or pharmacist.

Night-time, weekends, public holidays

24/7 pharmacies for sprain

Sprain doesn't keep office hours. If you need a medicine at 2 a.m. or at the weekend, open the map with the 24/7 filter switched on and look for the nearest on-duty pharmacy. Large cities have dozens of pharmacies open around the clock — below you have direct access to the list for each city, with address, phone number and verified opening hours.

Call before you set off, especially at night — on-duty rotas change and stock of some prescription medicines can be limited between deliveries.

Search the pharmacy

Medicine categories for sprain

Step by step

How to find a pharmacy fast for sprain

Open the interactive map and allow location access — you will immediately see pharmacies sorted by distance, each with its opening hours and a one-tap route in Google Maps. If it is night or the weekend, switch on the 24/7 filter to keep only the on-duty ones. For sprain many medicines are available over the counter, so you can go straight to the pharmacy without a prescription, but check availability on the price comparator first to avoid wasted trips.

If you have a preferred active substance (for example paracetamol or ibuprofen), search for it in the comparator before you leave — you will see which chain has it cheapest near you and whether it is in stock. If you have a repeat prescription, save your preferred pharmacy as a favourite in the app and turn on opening-hours notifications — it saves unnecessary trips, especially if treatment for sprain goes on for a while.

See also

Related symptoms and conditions

Frequently asked questions

What else would you like to know?

How long do I stay off a sprained leg?
Grade 1 — 1-2 weeks. Grade 2 — 3-6 weeks. Grade 3 — 6-12 weeks, possibly surgery. RICE during the first 48h.
Is an X-ray necessary?
Yes, for any inability to bear weight (the Ottawa rules), deformity, pain over specific bones — to rule out a fracture.
When can I apply ice?
During the first 48h, 15-20 min every 2-3h. Not directly on the skin — a towel in between. Not more than 20 min at a time (risk of frostbite).
Physiotherapy — when?
Start with passive mobilization after 3-5 days, active exercises at 7-10 days, muscle strengthening at 2-3 weeks. Crucial for preventing recurrence.

See also

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