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Psoriasis — what to take?

Psoriasis is a chronic inflammatory disease with erythematous-scaly plaques, keratinocyte hyperproliferation, associated with systemic comorbidities (arthritis, metabolic syndrome, depression).

5 recommended OTC drugs
~3,900 pharmacies available

OTC — no prescription

What you can take for psoriasis

Informativ. Nu înlocuiește sfatul medicului. Consultă medicul sau farmacistul înainte de a lua orice medicament.

Medical body content is still in Romanian:

Forms

Plaque psoriasis — 80%, on elbows, knees, scalp, sacrum. Guttate — small papules, post-infectious. Inverse — folds. Pustular, erythrodermic — severe. Nail psoriasis, psoriatic arthritis.

Treatment

Topical (mild-to-moderate forms):

  • Rich emollients — the foundation.
  • Topical corticosteroids (classes II-III).
  • Vitamin D analogues (calcipotriol — Daivonex, calcitriol).
  • Corticosteroid + calcipotriol combinations (Daivobet).
  • Tazarotene, anthralin.
  • Coal tar and salicylate shampoos for the scalp.

Systemic (moderate-severe forms, Rx):

  • Methotrexate.
  • Ciclosporin.
  • Retinoids (acitretin).
  • Apremilast.
  • Biologics: anti-TNF, anti-IL17 (secukinumab, ixekizumab), anti-IL23 (guselkumab, risankizumab).

Phototherapy narrowband UVB — effective, good safety profile.

Comorbidities

Psoriatic arthritis (30%), metabolic syndrome, obesity, diabetes, cardiovascular disease, depression, inflammatory bowel disease. Active screening.

OTC and lifestyle

  • Rich emollients (10-20% urea).
  • Vitamin D3 — frequent deficiency.
  • Omega-3 — anti-inflammatory.
  • Probiotics.
  • Weight loss — improves.
  • Smoking cessation, limit alcohol.
  • Stress management.

Medical disclaimer: the information in this guide is for informational purposes only and does not replace advice from a doctor or pharmacist. For diagnosis and treatment, consult a healthcare professional.

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